Frostbite – Is tPA the best treatment?

I would like a comparative scientific research paper written about frostbite, specifically using the treatment tPA compared to traditional therapy, and if the use of tPA leads to more favorable outcomes. I would like a title page and a reference page, along with headings throughout the paper. The headings, in order, include: Introduction, Discussion, Analysis, Social Determinants of Health (how it impacts people of different socio-economic backgrounds), and Conclusion/Recommendations. Also, the references cannot be more than 10 years old